Concepedia

Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer

Cátia Moutinho, Anna Martínez‐Cardús, Cristina Santos, Valentín Navarro-Perez, Eva Martinez‐Balibrea, Eva Musulén, F. Javier Carmona, Andrea Sartore‐Bianchi, Andrea Cassingena, Salvatore Siena,

JNCI Journal of the National Cancer Institute · 2013 · 96 citations · 22 references

DOIFull text

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Abstract

These results provide a basis for future clinical studies to validate SRBC hypermethylation as a predictive marker for oxaliplatin resistance in colorectal cancer.

References

22

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

Hans‐Joachim Schmoll, Eric Van Cutsem, Alexander Stein et al. · Annals of Oncology · 2012 · 1.5K citations · Full text

, , +9

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

Manel Esteller · JNCI Journal of the National Cancer Institute · 2000 · 1.2K citations · Full text

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

Mauro Moroni, Silvio Veronese, Silvia Benvenuti et al. · The Lancet Oncology · 2005 · 948 citations

, , +9

Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer

Rosalyn A. Juergens, John Wrangle, Frank P. Vendetti et al. · Cancer Discovery · 2011 · 668 citations · Full text

Amplification of the <i>MET</i> Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

Alberto Bardelli, Simona Corso, Andrea Bertotti et al. · Cancer Discovery · 2013 · 654 citations · Full text

, , +17