Concepedia

Drug Binding Interactions in the Inner Cavity of hERG Channels: Molecular Insights from Structure-Activity Relationships of Clofilium and Ibutilide Analogs

Matthew Perry, Phillip J. Stansfeld, Joanne L. Leaney, Claire Wood, Marcel J. de Groot, Derek J. Leishman, Michael J. Sutcliffe, John S. Mitcheson

Molecular Pharmacology · 2005 · 83 citations · 32 references

DOI

Concepts

References

32

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

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The PyMOL Molecular Graphics System

Warren L. DeLano · Medical Entomology and Zoology · 2002 · 18.1K citations

, , +11

Comparative Protein Modelling by Satisfaction of Spatial Restraints

Andrej Šali, Tom L. Blundell · Journal of Molecular Biology · 1993 · 13.2K citations

, , +11

The Structure of the Potassium Channel: Molecular Basis of K <sup>+</sup> Conduction and Selectivity

D. Doyle, João H. Morais‐Cabral, Richard A. Pfuetzner et al. · Science · 1998 · 6.8K citations

, , +17

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.7K citations

, , +14