Joanne L. Leaney

Mechanism of hERG K⁺channel blockade by the fluoroquinolone antibiotic moxifloxacin

Ari Alexandrou, Rona S. Duncan, A SULLIVAN et al. · British Journal of Pharmacology · 2006 · 114 citations · Full text

The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

Joanne L. Leaney, Andrew Tinker · Proceedings of the National Academy of Sciences · 2000 · 103 citations · Full text

Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 °C: Cisapride versus dofetilide

James T. Milnes, Harry J. Witchel, Joanne L. Leaney et al. · Journal of Pharmacological and Toxicological Methods · 2010 · 96 citations

Drug Binding Interactions in the Inner Cavity of hERG Channels: Molecular Insights from Structure-Activity Relationships of Clofilium and Ibutilide Analogs

Matthew Perry, Phillip J. Stansfeld, Joanne L. Leaney et al. · Molecular Pharmacology · 2005 · 83 citations

The G Protein α Subunit Has a Key Role in Determining the Specificity of Coupling to, but Not the Activation of, G Protein-gated Inwardly Rectifying K+ Channels

Joanne L. Leaney, Graeme Milligan, Andrew Tinker · Journal of Biological Chemistry · 2000 · 76 citations · Full text