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Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.9K citations

Pharmacy, Medicinal Chemistry, Molecular Biology +16

Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site:  Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

Choung U. Kim, Willard Lew, Matthew A. Williams et al. · Journal of the American Chemical Society · 1997 · 1.1K citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute Influenza

John J. Treanor, Frederick G. Hayden, Peter S. Vrooman et al. · JAMA · 2000 · 1K citations

Pharmacy, Pharmacology, Pharmacotherapy +14

Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution

J.N. Varghese, W.G. Laver, Peter M. Colman · Nature · 1983 · 894 citations

Life Sciences, Biochemistry, Molecular Biology +12

Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-α-d-N-acetylneuraminate) substrate

M. Potier, L. Mameli, M. Bélisle et al. · Analytical Biochemistry · 1979 · 824 citations

Life Sciences, Pharmaceutical Analysis, Enzymology +4