Concepedia
The EMBO Journal · 1986 · 183 citations · 22 references
Open access
Life SciencesGeneticsMolecular BiologyCell DifferentiationHuman GeneticsMolecular EvolutionB Cell DevelopmentDifferentiationImmunoglobulin Gene SegmentsPre-b Cell StageRearrangement Frequency
22
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
Hitoshi Sakano, Richard A. Maki, Yoshikazu Kurosawa et al. · Nature · 1980 · 797 citations
Life Sciences, Immunology, Molecular Biology +11
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.
F W Alt, D Baltimore · Proceedings of the National Academy of Sciences · 1982 · 760 citations · Full text
Life Sciences, Genetics, Molecular Biology +14
Ordered rearrangement of immunoglobulin heavy chain variable region segments.
Frederick W. Alt, George D. Yancopoulos, T. Keith Blackwell et al. · The EMBO Journal · 1984 · 733 citations · Full text
Life Sciences, Immunology, Molecular Biology +12
Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines
George D. Yancopoulos, Stephen Desiderio, Michael Paskind et al. · Nature · 1984 · 639 citations
Life Sciences, Genetics, Molecular Biology +8
The immunoglobulin heavy chain variable region (Igh‐V) locus in the mouse. I. One hundred Igh‐V genes comprise seven families of homologous genes
Peter H. Brodeur, Roy Riblet · European Journal of Immunology · 1984 · 537 citations
Life Sciences, Genetics, Molecular Genetics +16