Concepedia

Rearrangement Frequency

Rearrangement Frequency is a quantitative metric in immunogenetics that measures the rate at which V(D)J recombination events occur at immunoglobulin gene loci during B-cell development, distinguishing it from other recombination assessments by its focus on the frequency of productive gene segment rearrangements.

235

Publications

13.9K

Citations

1.1K

Authors

357

Institutions

Publications per year

2017–2026

15

Parents

Publications

235

EFFECTIVE DEME SIZES DURING LONG-TERM EVOLUTION ESTIMATED FROM RATES OF CHROMOSOMAL REARRANGEMENT

Russell Lande · Evolution · 1979 · 753 citations

, , +12

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction

H.-P. Brezinschek, Ruth I. Brezinschek, Peter E. Lipsky · The Journal of Immunology · 1995 · 426 citations · Full text

, , +17

Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.

H.-P. Brezinschek, Sandra J. Foster, Ruth I. Brezinschek et al. · Journal of Clinical Investigation · 1997 · 362 citations · Full text

, , +17

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.

Serge Lebecque, Patricia J. Gearhart · The Journal of Experimental Medicine · 1990 · 322 citations · Full text

, , +14

Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements

Scott D. Boyd, Bruno Gaëta, Katherine Jackson et al. · The Journal of Immunology · 2010 · 264 citations · Full text

, , +17

1–5 of 235

Authors

1.1K

  1. PE
    Peter E. Lipsky

    The University of Texas Southwestern Medical Center, United States

    10 publications · 1.3K citations

    10

    h-index

  2. AJ
    Ann J. Feeney

    Scripps Research Institute, United States

    10 publications · 524 citations

    10

    h-index

  3. TD
    Thomas Dörner

    Charité - Universitätsmedizin Berlin, Germany

    10 publications · 976 citations

    10

    h-index

  4. JJ
    Jacques J. M. van Dongen

    Erasmus MC, Netherlands

    6 publications · 260 citations

    6

    h-index

  5. SJ
    Sandra J. Foster

    The University of Texas Southwestern Medical Center, United States

    6 publications · 797 citations

    6

    h-index

1–5 of 1.1K

Institutions

357

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    11 h-index

    39 publications

    4.8K citations

  2. Scripps Research Institute

    San Diego, United States

    10 h-index

    40 publications

    2.4K citations

  3. Tufts University

    Medford, United States

    8 h-index

    16 publications

    267 citations

  4. Columbia University

    New York, United States

    7 h-index

    26 publications

    1.4K citations

  5. Institut Pasteur

    Paris, France

    7 h-index

    25 publications

    779 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    27 publications

    1.4K citations

  7. University of Toronto

    Toronto, Canada

    7 h-index

    23 publications

    920 citations

  8. University of Chicago

    Chicago, United States

    6 h-index

    33 publications

    1.4K citations

1–8 of 357

Venues

  1. The Journal of Immunology

    JI · 45 publications · 2.6K citations

    29

    h-index

  2. Blood

    18 publications · 1.3K citations

    17

    h-index

  3. The Journal of Experimental Medicine

    19 publications · 1.2K citations

    15

    h-index

  4. European Journal of Immunology

    EJI · 17 publications · 810 citations

    14

    h-index

  5. PubMed

    Repository · 13 publications · 678 citations

    13

    h-index

1–5