Patricia J. Gearhart

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

Kathryn A. Pape, Justin J. Taylor, Robert W. Maul et al. · Science · 2011 · 552 citations · Full text

Adaptive Immune System, Serum Immunoglobulin, Immunology +18

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

Patricia J. Gearhart, Nelson D. Johnson, R. Douglas et al. · Nature · 1981 · 503 citations

Immunocytochemical Technique, Signal Transduction, Autoimmune Disease +12

DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

Xianmin Zeng, David B. Winter, Cynthia Kasmer et al. · Nature Immunology · 2001 · 419 citations

Immunogenetics, Protein Expression, Somatic Hypermutation +11

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.

Serge Lebecque, Patricia J. Gearhart · The Journal of Experimental Medicine · 1990 · 318 citations · Full text

J Immunoglobulin Gene, Genetics, Molecular Biology +19

Clusters of point mutations are found exclusively around rearranged antibody variable genes.

Patricia J. Gearhart, Daniel Bogenhagen · Proceedings of the National Academy of Sciences · 1983 · 229 citations · Full text

Reverse Genetics, Genetics, Molecular Biology +19