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Publication | Open Access

Haem oxygenase-1 down-regulates high mobility group box 1 and matrix metalloproteinases in osteoarthritic synoviocytes

DOIFull Paper Access

30

Citations

28

References

2010

Year

Isabel García-Arnandis, María Isabel Guillén, Miguel Angel Castejón, Francisco Gomar Sancho, María José Alcaraz
Lara D. Veeken

Abstract

We have provided direct evidence that HO-1 down-regulates MMP-1, -3 and HMGB1 in osteoarthritic synoviocytes. HO-1 may be a potential strategy to control inflammatory and degradative processes in the progression of OA.

References

YearCitations

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