Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B

Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity

Jiazhi Sun, Michelle A. Blaskovich, Richard Jove et al. · Oncogene · 2005 · 262 citations

Medicine, Medicinal Chemistry, Pharmacology +5

Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells

Tehila Tannin-Spitz, Shlomo Grossman, Sara Dovrat et al. · Biochemical Pharmacology · 2006 · 215 citations

Medicine, Oncology, Pharmacology +7

Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells

Hiroyuki Fuke, Katsuya Shiraki, Kazushi Sugimoto et al. · Biochemical and Biophysical Research Communications · 2007 · 89 citations

Life Sciences, Oncology, Pharmacology +14

Stat3 up-regulates expression of nicotinamide N-methyltransferase in human cancer cells

Mikio Tomida, Hideki Ohtake, Takashi Yokota et al. · Journal of Cancer Research and Clinical Oncology · 2007 · 83 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN

Xiaoxia Sun, Jian Zhang, Lihua Wang et al. · Cancer Letters · 2008 · 80 citations

Life Sciences, Oncology, Pharmacology +13