Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics - Concepedia

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Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

360

Citations

31

References

2005

Year

Mikko Niemi, Janne T. Backman, Lauri Kajosaari, Julian Leathart, Mikko Neuvonen, Ann K. Daly, Michel Eichelbaum, K KIVISTO, Pertti J. Neuvonen

Clinical Pharmacology & Therapeutics

Abstract

Genetic polymorphism in SLCO1B1 is a major determinant of interindividual variability in the pharmacokinetics of repaglinide. The effect of SLCO1B1 polymorphism on the pharmacokinetics of repaglinide may be clinically important.

References

	Year	Citations

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