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Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies

Knockout MouseAlzheimer's DiseaseTransgenic Mouse ModelsMedicinePassive ImmunizationImmunologyN-terminal Projection DomainDegenerative PathologyAutoimmunityAlzheimer DiseaseImmunotherapyNeuroimmunologyCell BiologyImmunological Memory