Concepedia

Effect of the Fluoroquinolone Antibacterial Agent DX-619 on the Apparent Formation and Renal Clearances of 6β-Hydroxycortisol, an Endogenous Probe for CYP3A4 Inhibition, in Healthy Subjects

Yuichiro Imamura, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Katsuhisa Inoue, Hiroaki Yuasa, Takashi Izumi, Hiroyuki Kusuhara, Yuichi Sugiyama

Pharmaceutical Research · 2012 · 28 citations · 28 references

DOI

Concepts

References

28

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

Kazumitsu Ueda, Noboru Okamura, Midori Hirai et al. · Journal of Biological Chemistry · 1992 · 676 citations · Full text

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Terfenadine-Ketoconazole Interaction

Peter K. Honig · JAMA · 1993 · 658 citations

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A human transporter protein that mediates the final excretion step for toxic organic cations

Masato Otsuka, Takuya Matsumoto, Riyo Morimoto et al. · Proceedings of the National Academy of Sciences · 2005 · 566 citations · Full text

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Validation of a Rapid Equilibrium Dialysis Approach for the Measurement of Plasma Protein Binding

Nigel J. Waters, Rachel L. Jones, Gareth Williams et al. · Journal of Pharmaceutical Sciences · 2008 · 308 citations

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Differential Induction of Prehepatic and Hepatic Metabolism of Verapamil by Rifampin

Martin F. Fromm, Dagmar Busse, H. Kroemer et al. · Hepatology · 1996 · 281 citations · Full text

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