Nobuyuki Murayama

Prediction of in Vivo Potential for Metabolic Activation of Drugs into Chemically Reactive Intermediate:  Correlation of in Vitro and in Vivo Generation of Reactive Intermediates and in Vitro Glutathione Conjugate Formation in Rats and Humans

Noriko Masubuchi, Chie Makino, Nobuyuki Murayama · Chemical Research in Toxicology · 2007 · 124 citations

Pharmacotherapy, Toxicological Mechanism, Oxidative Stress +18

Prediction of Fluoroquinolone-Induced Elevation in Serum Creatinine Levels: A Case of Drug–Endogenous Substance Interaction Involving the Inhibition of Renal Secretion

Yoshinori Imamura, Nobuyuki Murayama, Noriko Okudaira et al. · Clinical Pharmacology & Therapeutics · 2010 · 106 citations

Prediction of Human Pharmacokinetics of Therapeutic Monoclonal Antibodies from Simple Allometry of Monkey Data

Masataka Oitate, Noriko Masubuchi, Takashi Ito et al. · Drug Metabolism and Pharmacokinetics · 2011 · 78 citations

6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects

Yuichiro Imamura, Yuri Tsuruya, Katja Damme et al. · Drug Metabolism and Disposition · 2014 · 59 citations

Tolerability, pharmacokinetics, and pharmacodynamics of DX-9065a, a new synthetic potent anticoagulant and specific factor Xa inhibitor, in healthy male volunteers

Nobuyuki Murayama, Makoto Tanaka, Satoshi Kunitada et al. · Clinical Pharmacology & Therapeutics · 1999 · 50 citations