Katsuhisa Inoue

Effects of a MATE Protein Inhibitor, Pyrimethamine, on the Renal Elimination of Metformin at Oral Microdose and at Therapeutic Dose in Healthy Subjects

Hiroyuki Kusuhara, S Ito, Yoshito Kumagai et al. · Clinical Pharmacology & Therapeutics · 2011 · 215 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Competitive Inhibition of the Luminal Efflux by Multidrug and Toxin Extrusions, but Not Basolateral Uptake by Organic Cation Transporter 2, Is the Likely Mechanism Underlying the Pharmacokinetic Drug-Drug Interactions Caused by Cimetidine in the Kidney

Sumito Ito, Hiroyuki Kusuhara, Miyu Yokochi et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 210 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Nitrosothiol Formation Catalyzed by Ceruloplasmin

Katsuhisa Inoue, Takaaki Akaike, Hiroshi Maeda · Journal of Biological Chemistry · 1999 · 201 citations · Full text

Life Sciences, Biochemistry, Chemistry +15

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

Hirotaka Matsuo, Ken Yamamoto, Hirofumi Nakaoka et al. · Annals of the Rheumatic Diseases · 2015 · 184 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Potent and Specific Inhibition of mMate1-Mediated Efflux of Type I Organic Cations in the Liver and Kidney by Pyrimethamine

Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 155 citations

Medicine, Biochemistry, Pharmacology +17