Takaaki Akaike

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

Tomoaki Ida, Tomohiro Sawa, Hideshi Ihara et al. · Proceedings of the National Academy of Sciences · 2014 · 917 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

AUTACs: Cargo-Specific Degraders Using Selective Autophagy

Daiki Takahashi, Jun Moriyama, Tomoe Y. Nakamura et al. · Molecular Cell · 2019 · 613 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Takaaki Akaike, Tomoaki Ida, Fan‐Yan Wei et al. · Nature Communications · 2017 · 543 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Keap1 degradation by autophagy for the maintenance of redox homeostasis

Keiko Taguchi, Nanako Fujikawa, Masaaki Komatsu et al. · Proceedings of the National Academy of Sciences · 2012 · 476 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Early Phase Tumor Accumulation of Macromolecules: A Great Difference in Clearance Rate between Tumor and Normal Tissues

Youichiro Noguchi, Jun Wu, Ruth Duncan et al. · Japanese Journal of Cancer Research · 1998 · 463 citations · Full text

Medicine, Oncology, Pharmacology +14