Concepedia

An efficient sequence for the preparation of small secondary amine hydrochloride salts for focused library generation without need for distillation or chromatographic purification

Gene M. Dubowchik, Jodi A. Michne, Dmitry Zuev

Bioorganic & Medicinal Chemistry Letters · 2004 · 12 citations · 5 references

References

5

Selective reductions. XVIII. Fast reaction of primary, secondary, and tertiary amides with diborane. Simple, convenient procedure for the conversion of amides to the corresponding amines

Herbert C. Brown, Peter Heim · The Journal of Organic Chemistry · 1973 · 185 citations

Natural Sciences, Chemistry, Mass Spectrometric Analysis +5

Properties of sodium-bis-(2-methoxyethoxy)aluminiumhydride. I. Reduction of some organic functional groups

V. Bažant, M. Čapka, M. Černý et al. · Tetrahedron Letters · 1968 · 65 citations

Natural Sciences, Chemistry, Organic Chemistry +5

Rapid Microscale Synthesis, a New Method for Lead Optimization Using Robotics and Solution Phase Chemistry: Application to the Synthesis and Optimization of Corticotropin-Releasing Factor<sub>1</sub>Receptor Antagonists

Jeffrey P. Whitten, Yun Feng Xie, Philip E. Erickson et al. · Journal of Medicinal Chemistry · 1996 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

ChemInform Abstract: Combinatorial Chemistry and Contemporary Pharmacology

J S Lazo, Peter Wipf · ChemInform · 2000 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Generation of Secondary Alkyl Amines on Solid Support by Borane Reduction: Application to the Parallel Synthesis of PPAR Ligands

Peter J. Brown, Kevin P. Hurley, L. William Stuart et al. · Synthesis · 1997 · 18 citations

Pharmacy, Chemistry, Medicinal Chemistry +17