Concepedia

Assurance of mitochondrial integrity and mammalian longevity by the p62–Keap1–Nrf2–Nqo1 cascade

Jeongho Kwon, Eunhye Park Han, Chi‐Bao Bui, Woo-Chul Shin, Jun Ho Lee, Sejeong Lee, Young‐Bong Choi, Ann–Hwee Lee, Kyong‐Hoon Lee, Chankyu Park,

EMBO Reports · 2012 · 138 citations · 21 references

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21

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat et al. · Nature Cell Biology · 2010 · 2.8K citations

, , +12

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, Satoshi Waguri, Keiko Taguchi et al. · Nature Cell Biology · 2010 · 2.4K citations

, , +14

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Martin Holzenberger, Joëlle Dupont, Bertrand Ducos et al. · Nature · 2002 · 2.1K citations · Full text

, , +12

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

DA Bass, J. Wallace Parce, Lawrence R. DeChatelet et al. · The Journal of Immunology · 1983 · 1.8K citations · Full text

, , +16

p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

Ashish Jain, Trond Lamark, Eva Sjøttem et al. · Journal of Biological Chemistry · 2010 · 1.5K citations · Full text

, , +17