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Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors

Jinyou Xu, Hyun Ok, Edward J. Gonzalez, Lawrence F. Colwell, Bahanu Habulihaz, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Frank Marsilio, Reshma A. Patel,

Bioorganic & Medicinal Chemistry Letters · 2004 · 76 citations · 22 references

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22

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study

Mette Zander, Sten Madsbad, Jan Lysgaard Madsen et al. · The Lancet · 2002 · 1.3K citations

, , +16

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(<i>S</i>)-pyrrolidine:  A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Edwin B. Villhauer, J. A. Brinkman, Goli B. Naderi et al. · Journal of Medicinal Chemistry · 2003 · 613 citations · Full text

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The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acids

David A. Evans, Thomas C. Britton, Jonathan A. Ellman et al. · Journal of the American Chemical Society · 1990 · 451 citations

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Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes

Expert Opinion on Investigational Drugs · 2003 · 208 citations

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Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes

Daniel J. Drucker · Expert Opinion on Investigational Drugs · 2003 · 204 citations

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