Concepedia

Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models

Jun‐Yan Liu, Yan-ping Lin, Hong Qiu, Christophe Morisseau, Tristan E. Rose, Sung Hee Hwang, Nipavan Chiamvimonvat, Bruce D. Hammock

European Journal of Pharmaceutical Sciences · 2013 · 70 citations · 34 references

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References

34

Soluble Epoxide Hydrolase Regulates Hydrolysis of Vasoactive Epoxyeicosatrienoic Acids

Zhigang Yu, Fengyun Xu, Linn M. Huse et al. · Circulation Research · 2000 · 466 citations

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

Kara Schmelzer, Lukáš Kubala, John W. Newman et al. · Proceedings of the National Academy of Sciences · 2005 · 439 citations · Full text

Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension

John D. Imig, Xueying Zhao, Jorge H. Capdevila et al. · Hypertension · 2002 · 397 citations · Full text

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Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

Jun Yang, Kara Schmelzer, Katrin Georgi et al. · Analytical Chemistry · 2009 · 310 citations · Full text

An Orally Active Epoxide Hydrolase Inhibitor Lowers Blood Pressure and Provides Renal Protection in Salt-Sensitive Hypertension

John D. Imig, Xueying Zhao, Constantine Z. Zaharis et al. · Hypertension · 2005 · 250 citations · Full text

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