Concepedia

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia S. Schlehe, Yao Liang Wong, Dennis J. Selkoe, Sarah E. Rice, Judith A. Steen, Matthew J. LaVoie, Thomas L. Schwarz

Cell · 2011 · 1.2K citations · 40 references

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40

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori et al. · Nature · 1998 · 5.2K citations

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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Hereditary Early-Onset Parkinson's Disease Caused by Mutations in <i>PINK1</i>

Enza Maria Valente, Patrick M. Abou‐Sleiman, Viviana Caputo et al. · Science · 2004 · 3.5K citations · Full text

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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat et al. · Nature Cell Biology · 2010 · 2.8K citations

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