Reducing the Late Sodium Current Improves Cardiac Function during Sodium Pump Inhibition by Ouabain

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Donald M. Bers, Yujie Zhu · Journal of Cardiovascular Disease Research · 2010 · 1.6K citations

Natural Sciences, Biophysics, Physiology +14

Electrophysiological Effects of Ranolazine, a Novel Antianginal Agent With Antiarrhythmic Properties

Charles Antzelevitch, Luiz Belardinelli, Andrew C. Zygmunt et al. · Circulation · 2004 · 678 citations · Full text

Medicine, Cardiology, Pharmacology +17

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

Stefan Wagner, Nataliya Dybkova, Eva Rasenack et al. · Journal of Clinical Investigation · 2006 · 554 citations · Full text

Life Sciences, Cardiology, Cell Biology +17

Ouabain Interaction with Cardiac Na+/K+-ATPase Initiates Signal Cascades Independent of Changes in Intracellular Na+ and Ca2+ Concentrations

Jiang Liu, Jiang Tian, Michael Haas et al. · Journal of Biological Chemistry · 2000 · 389 citations

Life Sciences, Biochemistry, Physiology +12

Elevated Cytosolic Na ⁺ Decreases Mitochondrial Ca ²⁺ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes

Christoph Maack, Sonia Cortassa, Miguel A. Aon et al. · Circulation Research · 2006 · 365 citations · Full text

Life Sciences, Cell Biology, Physiology +17