Concepedia

Whole-cell Patch Clamp

Whole-Cell Patch Clamp is a variant of the patch-clamp electrophysiology technique in which the membrane patch underlying the recording pipette is ruptured to establish low-resistance electrical access to the entire cell interior, enabling measurement of the sum total of ionic currents across the cell membrane under voltage-clamp or current-clamp conditions.

3.2K

Publications

190.8K

Citations

11.2K

Authors

2K

Institutions

Publications per year

2017–2026

317

Variants

Whole-cell Patch-clamp

Parents

Publications

3.2K

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

R Horn, Alain Marty · The Journal of General Physiology · 1988 · 1.8K citations · Full text

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A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system

Frances A. Edwards, Arthur Konnerth, Bert Sakmann et al. · Pflügers Archiv - European Journal of Physiology · 1989 · 1.3K citations · Full text

, , +16

<scp>d</scp> -Serine is an endogenous ligand for the glycine site of the <i>N</i> -methyl- <scp>d</scp> -aspartate receptor

Jean‐Pierre Mothet, Angèle Parent, Herman Wolosker et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations · Full text

, , +17

Characteristics of Gintonin-Mediated Membrane Depolarization of Pacemaker Activity in Cultured Interstitial Cells of Cajal

Byung Joo Kim, Joo‐Hyun Nam, Kyun Ha Kim et al. · Cellular Physiology and Biochemistry · 2014 · 892 citations · Full text

, , +17

Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.

Stephen L. Archer, Jiehuan Huang, Václav Hampl et al. · Proceedings of the National Academy of Sciences · 1994 · 820 citations · Full text

, , +16

1–5 of 3.2K

Authors

11.2K

  1. SN
    Stanley Nattel

    Montreal Heart Institute, Canada

    22 publications · 2.8K citations

    21

    h-index

  2. BY
    Baofeng Yang

    Harbin Medical University, China

    20 publications · 923 citations

    17

    h-index

  3. ZW
    Zhiguo Wang

    Montreal Heart Institute, Canada

    15 publications · 1.6K citations

    15

    h-index

  4. TN
    Toshio Narahashi

    Northwestern University, United States

    14 publications · 1.3K citations

    14

    h-index

  5. YO
    Yasunobu Okada

    National Institute for Physiological Sciences, Japan

    15 publications · 884 citations

    14

    h-index

1–5 of 11.2K

Institutions

2K

  1. Yale University

    New Haven, United States

    40 h-index

    150 publications

    15.9K citations

  2. Inserm

    Paris, France

    38 h-index

    214 publications

    12.4K citations

  3. University of Pennsylvania

    Philadelphia, United States

    32 h-index

    99 publications

    8.1K citations

  4. University of Alabama at Birmingham

    Birmingham, United States

    31 h-index

    129 publications

    10.3K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    29 h-index

    170 publications

    8.1K citations

  6. University of California, Los Angeles

    Los Angeles, United States

    25 h-index

    116 publications

    8.7K citations

  7. National Institutes of Health

    Bethesda, United States

    25 h-index

    97 publications

    6.8K citations

  8. Cornell University

    Ithaca, United States

    25 h-index

    79 publications

    5K citations

1–8 of 2K

Venues

  1. Journal of Neuroscience

    174 publications · 20K citations

    89

    h-index

  2. The Journal of Physiology

    212 publications · 15.2K citations

    74

    h-index

  3. Journal of Neurophysiology

    JN · 241 publications · 13.4K citations

    67

    h-index

  4. Circulation Research

    92 publications · 10.2K citations

    57

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 71 publications · 11.5K citations

    55

    h-index

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