Concepedia

Late Sodium Current

Late Sodium Current is a persistent inward sodium ion current that occurs during the plateau phase of the cardiac action potential, distinguished from the transient sodium current by its prolonged activation and contribution to cellular depolarization and arrhythmogenesis.

360

Publications

21K

Citations

1.7K

Authors

460

Institutions

Publications per year

2017–2026

81

Variants

InalLate Sodium Current (Inal)

Parents

Publications

360

Mutant Caveolin-3 Induces Persistent Late Sodium Current and Is Associated With Long-QT Syndrome

Matteo Vatta, Michael J. Ackerman, Bin Ye et al. · Circulation · 2006 · 553 citations · Full text

, , +17

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart

Carmen R. Valdivia, William W. Chu, Jielin Pu et al. · Journal of Molecular and Cellular Cardiology · 2005 · 444 citations

, , +16

Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy

Raffaele Coppini, Cecilia Ferrantini, Lina Yao et al. · Circulation · 2012 · 426 citations · Full text

, , +16

Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

Luiz Belardinelli · Heart · 2006 · 387 citations · Full text

, , +17

Novel, Ultraslow Inactivating Sodium Current in Human Ventricular Cardiomyocytes

Victor A. Maltsev, Hani N. Sabbah, Robert Higgins et al. · Circulation · 1998 · 308 citations · Full text

, , +17

1–5 of 360

Authors

1.7K

  1. LB
    Luiz Belardinelli

    Gilead Sciences (United States), United States

    65 publications · 4.7K citations

    36

    h-index

  2. SR
    Sridharan Rajamani

    Gilead Sciences (United States), United States

    24 publications · 966 citations

    20

    h-index

  3. JC
    John C. Shryock

    University of Florida, United States

    19 publications · 1.7K citations

    17

    h-index

  4. JM
    Jihua Ma

    Wuhan University of Science and Technology, China

    13 publications · 372 citations

    12

    h-index

  5. VA
    Victor A. Maltsev

    National Institute on Aging, United States

    12 publications · 1.2K citations

    12

    h-index

1–5 of 1.7K

Institutions

460

  1. Gilead Sciences (United States)

    Foster City, United States

    29 h-index

    225 publications

    16.9K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    59 publications

    5.2K citations

  3. University of Wisconsin–Madison

    Madison, United States

    12 h-index

    56 publications

    10.1K citations

  4. Wuhan University of Science and Technology

    Wuhan, China

    12 h-index

    97 publications

    3K citations

  5. University of Göttingen

    Göttingen, Germany

    11 h-index

    64 publications

    5.5K citations

  6. Henry Ford Hospital

    Detroit, United States

    11 h-index

    31 publications

    4K citations

  7. University of Florida

    Gainesville, United States

    11 h-index

    20 publications

    2.1K citations

  8. Masonic Medical Research Laboratory

    Utica, United States

    11 h-index

    40 publications

    2.3K citations

1–8 of 460

Venues

  1. Journal of Molecular and Cellular Cardiology

    25 publications · 1.9K citations

    22

    h-index

  2. Heart Rhythm

    23 publications · 1.3K citations

    20

    h-index

  3. 17

    h-index

  4. 15

    h-index

  5. Cardiovascular Research

    CVR · 15 publications · 1.1K citations

    15

    h-index

1–5