Inhibition of Phorbol Ester–Induced COX-2 Expression by Epigallocatechin Gallate in Mouse Skin and Cultured Human Mammary Epithelial Cells

p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes

Jonathan L. E. Dean, Matthew Brook, Andrew R. Clark et al. · Journal of Biological Chemistry · 1999 · 492 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Green Tea Polyphenol Epigallocatechin-3-Gallate Differentially Modulates Nuclear Factor κB in Cancer Cells versus Normal Cells

Nihal Ahmad, Sanjay Gupta, Hasan Mukhtar · Archives of Biochemistry and Biophysics · 2000 · 422 citations

Medicine, Oncology, Pharmacology +12

Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.

Ritesh Agarwal, Santosh K. Katiyar, S. I. A. Zaidi et al. · PubMed · 1992 · 417 citations

Pharmacy, Pharmacology, Toxicology +16

Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.

Z Dong, W Ma, Chuanshu Huang et al. · PubMed · 1997 · 351 citations

Medicine, Oncology, Pharmacology +15

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Howard F. Tiano, Charles D. Loftin, Jackie Akunda et al. · PubMed · 2002 · 345 citations

Medicine, Dermatology, Cancer Pharmacology +7