Matthew Brook

p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes

Jonathan L. E. Dean, Matthew Brook, Andrew R. Clark et al. · Journal of Biological Chemistry · 1999 · 492 citations · Full text

Immunology, Cell Death, P38 Mapk +20

Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Kamal R Mahtani, Matthew Brook, Jonathan L. E. Dean et al. · Molecular and Cellular Biology · 2001 · 446 citations · Full text

Inflammation, Cytokine, Signal Transduction Pathways +13

Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element

Edward Hitti, Tatiana Iakovleva, Matthew Brook et al. · Molecular and Cellular Biology · 2006 · 385 citations · Full text

Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38

Marina Lasa, Matthew Brook, Jeremy Saklatvala et al. · Molecular and Cellular Biology · 2001 · 256 citations · Full text

Immunology, Cell Death, Oxidative Stress +19

Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways

Matthew Brook, Carmen R. Tchen, Tomàs Santalucı́a et al. · Molecular and Cellular Biology · 2006 · 246 citations · Full text

Molecular Biology, P38 Mapk, Tristetraprolin Subcellular Localization +18