Concepedia

Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells

Hironori Fujiwara, Kimihiro Matsunaga, Mika Saito, Shinji Hagiya, Ken‐Ichi Furukawa, Hideshi Nakamura, Yasushi Ohizumi

European Journal of Pharmacology · 2001 · 58 citations · 31 references

DOI

Concepts

References

31

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

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The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

Okezie I. Aruoma, Barry Halliwell, Brigid M. Hoey et al. · Free Radical Biology and Medicine · 1989 · 1.8K citations

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Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

Ryoji Yao, Geoffrey M. Cooper · Science · 1995 · 1.4K citations

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Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil et al. · Molecular and Cellular Biology · 1996 · 680 citations · Full text

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Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase.

Koutarou D. Kimura, Satoshi Hattori, Yukihito Kabuyama et al. · Journal of Biological Chemistry · 1994 · 335 citations · Full text

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