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Publication | Open Access

Hypoxia Induces Dilated Cardiomyopathy in the Chick Embryo: Mechanism, Intervention, and Long-Term Consequences

DOIFull Paper Access

140

Citations

35

References

2009

Year

Andrei N. Tintu, Ellen V. Rouwet, Stefan Verlohren, Joep Brinkmann, Shakil Ahmad, F. Crispi, Marc van Bilsen, Peter Carmeliet, Anne Cathrine Staff, Marc Tjwa,
PLoS ONE

Abstract

Our data show that hypoxia causes a decreased cardiac performance and cardiomyopathy in chick embryos, involving a significant VEGF-mediated component. This cardiomyopathy persists into adulthood.

References

YearCitations

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