Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target

Small heat shock proteins are molecular chaperones.

Ursula Jakob, Matthias Gaestel, Katrin Engel et al. · Journal of Biological Chemistry · 1993 · 1.4K citations · Full text

Murine Hsp25, Protein Chemistry, Molecular Chaperones +14

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

Robert L. Chevalier, Michael S. Forbes, Barbara A. Thornhill · Kidney International · 2009 · 1K citations

Glomerular Disease, Urology, Renal Disease +14

Hsp27 negatively regulates cell death by interacting with cytochrome c

Jean‐Marie Bruey, Cécile Ducasse, Philippe Bonniaud et al. · Nature Cell Biology · 2000 · 977 citations

Signal Transduction, Cell Regulation, Molecular Pathway +8

Crystal structure of a small heat-shock protein

Kyeong Kyu Kim, Rosalind Kim, Sung‐Hou Kim · Nature · 1998 · 889 citations

Crystal Structure, Protein X-ray Crystallography, Molecular Biology +3

Regulation of Hsp27 Oligomerization, Chaperone Function, and Protective Activity against Oxidative Stress/Tumor Necrosis Factor α by Phosphorylation

Thorsten Rogalla, Monika Ehrnsperger, Xavier Préville et al. · Journal of Biological Chemistry · 1999 · 734 citations · Full text