Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker, +3

Critical Care Medicine

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre, +8

New England Journal of Medicine

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

Osamu Takeuchi, Katsuaki Hoshino, Taro Kawai, +5

Immunity

Toll-like ReceptorsGram-negative BacteriologyVirulence FactorPathogenesisBacteriology +5

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

R. Phillip Dellinger, Jean Carlet, Henry Masur, +11

Intensive Care Medicine

Trauma ResuscitationCritical Care ManagementSevere SepsisAcute CarePatient Safety +7

Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock

Djillali Annane

JAMA

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

Richard S. Hotchkiss, Paul E. Swanson, Bradley D. Freeman, +5

Critical Care Medicine

Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes

Axel Bouchon, Jes Dietrich, Marco Colonna

The Journal of Immunology

Treatment of Septic Shock with the Tumor Necrosis Factor Receptor:Fc Fusion Protein

Charles J. Fisher, Jan M. Agosti, Steven M. Opal, +6

New England Journal of Medicine

Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock*

Yasser Sakr, Marc‐Jacques Dubois, Daniel De Backer, +2

Critical Care Medicine

Enhanced Th1 Activity and Development of Chronic Enterocolitis in Mice Devoid of Stat3 in Macrophages and Neutrophils

Kiyoshi Takeda, Björn E. Clausen, Tsuneyasu Kaisho, +4

Immunity

InflammationCytokineMice DevoidImmunologyImmune Regulation +8