A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells - Concepedia

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A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

DOI Full Paper Access

148

Citations

26

References

2010

Year

Li Lin, Stephanie Deangelis, Elizabeth Foust, James R. Fuchs, Chenglong Li, Pui‐Kai Li, Eric Schwartz, Gregory B. Lesinski, Don Benson, Jiagao Lü,

Molecular Cancer

Abstract

Our findings indicate that FLLL32 exhibits potent inhibitory activity to STAT3 and has potential for targeting multiple myeloma, glioblastoma, liver cancer, and colorectal cancer cells expressing constitutive STAT3 signaling.

References

	Year	Citations

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