Concepedia

The role of TNF-α and PAI-1 gene polymorphisms in familial Mediterranean fever

Munis Dündar, Aslıhan Kiraz, Burhan Balta, Elif Funda Emirogullari, Gökmen Zararsız, Alper Yurçi, Duran Aslan, Mevlüt Başkol

Modern Rheumatology · 2012 · 14 citations · 21 references

DOI

Abstract

Screening with PAI-1 gene polymorphism tests may be beneficial for tracing future FMF patients. However, further investigations are needed to reach a conclusion on the association between PAI-1 polymorphisms and FMF.

References

21

Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation

Anthony G. Wilson, Julian Symons, Tarra L. McDowell et al. · Proceedings of the National Academy of Sciences · 1997 · 2.2K citations · Full text

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The −308 tumor necrosis factor-α promoter polymorphism effects transcription

Karen M. Kroeger, Kylie Carville, Lawrence J. Abraham · Molecular Immunology · 1997 · 861 citations

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Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

Jae Jin Chae, Young-Hun Cho, Geun‐Shik Lee et al. · Immunity · 2011 · 446 citations · Full text

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Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo

Matthew J. Flick, XinLi Du, David P. Witte et al. · Journal of Clinical Investigation · 2004 · 435 citations · Full text

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Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta production

Joost P.H. Drenth, Stan HM van Uum, Marcel van Deuren et al. · Journal of Applied Physiology · 1995 · 292 citations