Matthew J. Flick

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell–mediated elimination of tumor cells

Joseph S. Palumbo, Kathryn E. Talmage, Jessica V. Massari et al. · Blood · 2004 · 974 citations · Full text

Impaired wound healing in mice with a disrupted plasminogen gene

John Rømer, Thomas H. Bugge, Charles Fyke et al. · Nature Medicine · 1996 · 563 citations

Inflammation, Immunology, Wound Care +9

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.

Thomas H. Bugge, Matthew J. Flick, Cynthia C. Daugherty et al. · Genes & Development · 1995 · 441 citations · Full text

Genetics, Plasminogen Deficiency, Immunology +20

Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo

Matthew J. Flick, XinLi Du, David P. Witte et al. · Journal of Clinical Investigation · 2004 · 435 citations · Full text

Immunology, Cell Death, Pathology +23

Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency

Thomas Bugge, Keith W. Kombrinck, Matthew J. Flick et al. · Cell · 1996 · 424 citations · Full text

Inflammation, Knockout Mouse, Disease Mechanism +9