Concepedia

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

Sanjit K. Roy, Qinghe Chen, Junsheng Fu, Sharmila Shankar

PLoS ONE · 2011 · 127 citations · 30 references

DOIFull text

Open access

Abstract

These data suggest that inhibition of ERK and AKT pathways act together to activate FOXO transcription factors which are involved in resveratrol-mediated pancreatic tumor growth suppression.

References

30

Cancer Statistics, 2010

Ahmedin Jemal, Rebecca L. Siegel, Jiaquan Xu et al. · CA A Cancer Journal for Clinicians · 2010 · 12.6K citations · Full text

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

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Trastuzumab-Induced Hepatotoxicity: A Case Report

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

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