Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors - Concepedia

Concepedia

Publication | Open Access

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

DOI Full Paper Access

127

Citations

30

References

2011

Year

Sanjit K. Roy, Qinghe Chen, Junsheng Fu, Sharmila Shankar

Abstract

These data suggest that inhibition of ERK and AKT pathways act together to activate FOXO transcription factors which are involved in resveratrol-mediated pancreatic tumor growth suppression.

References

	Year	Citations
Cancer Statistics, 2010 Ahmedin Jemal, Rebecca L. Siegel, Jiaquan Xu, CA A Cancer Journal for Clinicians	2010	12.6K
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor Anne Brunet, Azad Bonni, Michael J. Zigmond, Cell Systems BiologySignal TransductionCell RegulationForkhead Transcription FactorSignaling Pathway	1999	6.5K
Trastuzumab-Induced Hepatotoxicity: A Case Report D. Vucicevic, Elizabeth J. Carey, Nina J. Karlin Breast Care	2013	4.4K
High Performance of <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography and Contrast-Enhanced CT in a Rapid Outpatient Diagnostic Program for Patients with Suspected Lung Cancer Pepijn Brocken, Erik H.F.M. van der Heijden, P.N.R. Dekhuijzen, Respiration	2013	4K
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein, Nature Histone ModificationsChromatinTranscriptional RegulationLifespan ExtensionChromatin Remodeling	2000	3.5K
Isolation of a transforming sequence from a human bladder carcinoma cell line Chiaho Shih, Robert A. Weinberg Cell UrologyGenitourinary CancerTumor HeterogeneityMedicineCancer Biology	1982	778
Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN Noriaki Nakamura, Shivapriya Ramaswamy, Francisca Vázquez, Molecular and Cellular Biology Forkhead Transcription FactorsApoptosisCell DeathAkt KinaseCell Cycle	2000	568
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal Pascale F. Dijkers, Kim U. Birkenkamp, Eric W.‐F. Lam, The Journal of Cell Biology	2002	362
Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily Michael J. Anderson, Carrie S. Viars, Suzanne Czekay, Genomics Developmental BiologyGeneticsGene StructureGenomic MechanismGenetic Mechanism	1998	353
Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice Tatsuo Furuyama, Kazuko Kitayama, Yuri Shimoda, Journal of Biological Chemistry	2004	334

Page 1