Concepedia

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Dongbo Yu, Hannah M. Pendergraff, Jing Liu, Holly Kordasiewicz, Don W. Cleveland, Eric E. Swayze, Walt F. Lima, Stanley T. Crooke, Thazha P. Prakash, David R. Corey

Cell · 2012 · 275 citations · 46 references

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46

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim, Nelson C. Lau, Philip W. Garrett-Engele et al. · Nature · 2005 · 4.8K citations

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

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Argonaute2 Is the Catalytic Engine of Mammalian RNAi

Jidong Liu, Michelle A. Carmell, Fabiola V. Rivas et al. · Science · 2004 · 2.7K citations

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Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs

Gunter Meister, Markus Landthaler, Agnieszka Patkaniowska et al. · Molecular Cell · 2004 · 1.9K citations · Full text

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