Concepedia

VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium

Tara Karnezis, Ramin Shayan, Carol Caesar, Sally Roufail, Nicole C. Harris, Kathryn Ardipradja, You Fang Zhang, Steven P. Williams, Rae H. Farnsworth, Ming G. Chai,

Cancer Cell · 2012 · 275 citations · 54 references

Open access

Concepts

MedicineCancer BiologyOncologyMetastasisSignal TransductionTumor MicroenvironmentAngiogenesisAngiogenesis In CancerGrowth Factor SignalingLymphatic MetastasisLymphatic MicroenvironmentTumor Microenvironment ModulationCancer Metastasis MechanismsLymphangiogenic SignalingMetastasis PromotionTumor Metastasis BiologyVascular Endothelial Growth Factor D Signaling

References

54

Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

Masahiko Tsujii, Sunao Kawano, Shingo Tsuji et al. · Cell · 1998 · 2.3K citations · Full text

Medicine, Cancer Biology, Oncology +14

Genes Expressed in Human Tumor Endothelium

Brad St. Croix, Carlo Rago, Victor E. Velculescu et al. · Science · 2000 · 1.8K citations

Medicine, Molecular Biology, Oncology +12

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

Mihaela Skobe, Thomas Hawighorst, David G. Jackson et al. · Nature Medicine · 2001 · 1.7K citations

Medicine, Cancer Biology, Oncology +16

A novel vascular endothelial growth factor, VEGF‐C, is a ligand for the Flt4 (VEGFR‐3) and KDR (VEGFR‐2) receptor tyrosine kinases.

Vladimir Joukov, Katri Pajusola, Arja Kaipainen et al. · The EMBO Journal · 1996 · 1.7K citations · Full text

Life Sciences, Cell Biology, Pharmacology +11

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

Michael Jeltsch, Arja Kaipainen, Vladimir Joukov et al. · Science · 1997 · 1.3K citations · Full text

Medicine, Immunology, Oncology +17