Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

Mihaela Skobe, Thomas Hawighorst, David G. Jackson, +7

Nature Medicine

Breast OncologyMammary Gland DevelopmentMedicineCell ProliferationBreast Cancer +8

Concurrent Induction of Lymphangiogenesis, Angiogenesis, and Macrophage Recruitment by Vascular Endothelial Growth Factor-C in Melanoma

Mihaela Skobe, Leena M. Hamberg, Thomas Hawighorst, +4

American Journal Of Pathology

AngiogenesisMedicineConcurrent InductionMelanomaImmunology +5

Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis

Michael Streit, Lucia Riccardi, Paula Velasco, +4

Proceedings of the National Academy of Sciences

ThrombopoiesisThrombosisAngiogenesisMedicineTumor Growth +13

Activation of the Tie2 Receptor by Angiopoietin-1 Enhances Tumor Vessel Maturation and Impairs Squamous Cell Carcinoma Growth

Thomas Hawighorst, Mihaela Skobe, Michael Streit, +6

American Journal Of Pathology

Tumor BiologyAngiogenesisMedicineTie2 ReceptorPathology +8

Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice

Thomas Hawighorst, Hajimu Oura, Michael Streit, +6

Oncogene

AngiogenesisMedicineImmunologyTumor LymphangiogenesisVascular Biology +8

CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo

Manuel Koch, F Hussein, A Woeste, +4

Breast Cancer Research and Treatment

N-terminal Recombinant FragmentApoptosisImmunologyCell DeathTumor Biology +16

Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.

Michael Streit, Antonia E. Stephen, Thomas Hawighorst, +5

PubMed

Tissue EngineeringCell TherapyEngineeringContinuous AdministrationBiomedical Engineering +15

The Angiogenesis Inhibitor Vasostatin does not Impair Wound Healing at Tumor-Inhibiting Doses

Bernhard Lange‐Asschenfeldt, Paula Velasco, Michael Streit, +4

Journal of Investigative Dermatology

Angiogenesis Inhibitor VasostatinAngiogenesisMedicineTumor-inhibiting DosesPharmacology +9

Expression of the Type-1 Repeats of Thrombospondin-1 Inhibits Tumor Growth Through Activation of Transforming Growth Factor-β

Karen O. Yee, Michael Streit, Thomas Hawighorst, +2

American Journal Of Pathology

MedicineType-1 RepeatsTransforming Growth Factor-βPathologyCancer Cell Biology +8

Medroxyprogesterone acetate inhibits the proliferation of estrogen- and progesterone-receptor negative MFM-223 human mammary cancer cells via the androgen receptor

Reinhard Hackenberg, Thomas Hawighorst, Angelika Filmer, +2

Breast Cancer Research and Treatment

Androgen ReceptorMedroxyprogesterone AcetateBreast OncologyMedicineHormonal Receptor +6