A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

Vladimir Joukov, Katri Pajusola, Arja Kaipainen, +6

The EMBO Journal

AngiogenesisReceptor Tyrosine KinaseImmunologyEndothelial DysfunctionVascular Biology +7

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

Arja Kaipainen, Jaana Korhonen, Tuija Mustonen, +5

Proceedings of the National Academy of Sciences

Flt4 SignalImmunologyFlt4 MrnaAngiogenesisSignaling Pathway +15

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

Michael Jeltsch, Arja Kaipainen, Vladimir Joukov, +7

Science

Vegf Receptors Vegfr-3ImmunologyPathologyDermatologyVegf-c Transgenic Mice +16

Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

Berit Olofsson, Katri Pajusola, Arja Kaipainen, +7

Proceedings of the National Academy of Sciences

Placenta Growth FactorAngiogenesisDevelopmental BiologyEndothelial CellsBone Morphogenic Protein +12

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

Eric G. Bluemn, Ilsa M. Coleman, Jared M. Lucas, +24

Cancer Cell

UrologyHormonal ReceptorFibroblast Growth FactorFgf SignalingProstatic Disease +2

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

Liisa Pertovaara, Arja Kaipainen, Tuija Mustonen, +4

Journal of Biological Chemistry

Endothelial CellsGrowth Factor-betaCellular PhysiologyAngiogenesisGrowth Factor Beta +14

VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development

Eola Kukk, Athina Lymboussaki, Suvi Taira, +4

Development

Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer

Mark P. Labrecque, Ilsa M. Coleman, Lisha G. Brown, +19

Journal of Clinical Investigation

Scnpc Pdx ModelsUrologyStratifies Diverse PhenotypesGenitourinary CancerTumor Heterogeneity +13

PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis

Dipak Panigrahy, Samuel Singer, Lucy Q. Shen, +12

Journal of Clinical Investigation

Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3.

Lotta Jussila, Reija Valtola, Taina A. Partanen, +9

PubMed

Endothelial CellsImmunologyPathologyTumor BiologyAngiogenesis +15