Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

Akash Kumar, Ilsa M. Coleman, Colm Morrissey, +20

Nature Medicine

Disease HeterogeneityMetastatic Prostate CancerUrologyGenitourinary CancerTumor Heterogeneity +5

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

Eric G. Bluemn, Ilsa M. Coleman, Jared M. Lucas, +24

Cancer Cell

UrologyHormonal ReceptorFibroblast Growth FactorFgf SignalingProstatic Disease +2

The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis

Jared M. Lucas, Cynthia Heinlein, Tom Kim, +15

Cancer Discovery

Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts

Stephanie Bertram, Adeline Heurich, Hayley Lavender, +7

PLoS ONE

Protease InhibitorsAllergyHuman RespiratoryPorcine Tmprss2Multiple Sites +11

A causal role for ERG in neoplastic transformation of prostate epithelium

Olga Klezovitch, Michael Risk, Ilsa M. Coleman, +5

Proceedings of the National Academy of Sciences

UrologyPerineural InvasionSignaling PathwayEpithelial CellsErg Protein +13

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Michael D. Nyquist, Alexandra Corella, Ilsa M. Coleman, +14

Cell Reports

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Xiaotun Zhang, Ilsa M. Coleman, Lisha G. Brown, +15

Clinical Cancer Research

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors

Liem T. Nguyen, Maria Tretiakova, Mark R. Silvis, +9

Cancer Cell

Yap1 Transcriptional ProgramTranscriptional RegulationUrologySignal TransductionAge-related Prostate Tumors +8

Supraphysiological androgens suppress prostate cancer growth through androgen receptor–mediated DNA damage

Payel Chatterjee, Michael T. Schweizer, Jared M. Lucas, +12

Journal of Clinical Investigation

Androgen ReceptorGenome InstabilityUrologyDna DamageHormonal Receptor +10

A molecular, morphometric and mechanical comparison of the structural elements of byssus from<i>Mytilus edulis</i>and<i>Mytilus galloprovincialis</i>

Jared M. Lucas, Eleonora Vaccaro, J. Herbert Waite

Journal of Experimental Biology

Mechanical ComparisonGeneticsCytoskeletonAnatomyComparative Anatomy +20