Concepedia

A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice

Vandana Saxena, Guorui Xie, Bei Li, Tierra R. Farris, Thomas Welte, Bin Gong, Ping Wu, Shao‐Jun Tang, Robert B. Tesh, Tian Wang

PLoS neglected tropical diseases · 2013 · 43 citations · 49 references

DOIFull text

Open access

Abstract

WNV H8912 is highly attenuated in both neuroinvasiveness and neurovirulence in mice. It induces a low and delayed anti-viral response in mice and preferentially persists in the kidneys.

References

49

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

Sally R.M. Bennett, Freda Karamalis, Richard A. Flavell et al. · Nature · 1998 · 2.1K citations

, , +8

Origin of the West Nile Virus Responsible for an Outbreak of Encephalitis in the Northeastern United States

Robert S. Lanciotti, John T. Roehrig, Vincent Deubel et al. · Science · 1999 · 1.6K citations

, , +16

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

Tian Wang, Terrence Town, Lena Alexopoulou et al. · Nature Medicine · 2004 · 1.1K citations

, , +10

Rapid Detection of West Nile Virus from Human Clinical Specimens, Field-Collected Mosquitoes, and Avian Samples by a TaqMan Reverse Transcriptase-PCR Assay

Robert S. Lanciotti, Amy J. Kerst, Roger S. Nasci et al. · Journal of Clinical Microbiology · 2000 · 1.1K citations · Full text

Interleukin-10 determines viral clearance or persistence in vivo

David G. Brooks, Matthew J. Trifilo, Kurt H. Edelmann et al. · Nature Medicine · 2006 · 911 citations · Full text

, , +5