Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

Tian Wang, Terrence Town, Lena Alexopoulou, +3

Nature Medicine

NeurovirologyMedicinePathogenesisImmunologyViral Pathogenesis +8

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

Hongjie Xia, Huanle Luo, Chao Shan, +11

Nature Communications

Mosquito InfectionViral EvolutionHost Interferon InductionGeneticsPathogenesis +12

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

Justin M. Richner, Brett W. Jagger, Chao Shan, +20

Cell

VaccinationVaccinologyMaternal ImmunizationVaccine DevelopmentImmunology +2

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

Chao Shan, Antonio E. Muruato, Bruno Tardelli Diniz Nunes, +11

Nature Medicine

VaccinationVaccine DevelopmentImmunologyVirologyMouse Models +4

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Thomas Welte, Ik Sun Kim, Lin Tian, +23

Nature Cell Biology

Oncogenic AgentMedicineMyelopoiesisCell BiologyTumor Suppressor +6

Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing

Terrence Town, Fengwei Bai, Tian Wang, +6

Immunity

InflammationToll-like ReceptorsToll-like Receptor 7Innate Immune SystemImmunology +5

Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus Infection

Bimmi Shrestha, Tian Wang, Melanie A. Samuel, +4

Journal of Virology

Peripheral InfectionViral PersistenceGamma InterferonNeurovirologyWnv Infection +12

IFN-γ-Producing γδ T Cells Help Control Murine West Nile Virus Infection

Tian Wang, Eileen P. Scully, Zhinan Yin, +7

The Journal of Immunology

A chikungunya fever vaccine utilizing an insect-specific virus platform

Jesse H. Erasmus, Albert J. Auguste, Jason T. Kaelber, +10

Nature Medicine

VaccinationInsect VirusVaccine TargetImmunologyVirology +2

Functional Analysis of Glycosylation of Zika Virus Envelope Protein

Camila R. Fontes-Garfias, Chao Shan, Huanle Luo, +11

Cell Reports