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LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Ying Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov,

Neurobiology of Disease · 2013 · 271 citations · 19 references

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19

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

J. William Langston, Philip L. Ballard, James W. Tetrud et al. · Science · 1983 · 4.9K citations

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Ranjita Betarbet, Todd Sherer, Gillian M. MacKenzie et al. · Nature Neuroscience · 2000 · 3.6K citations · Full text

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Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3K citations · Full text

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Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

Coro Paisán‐Ruíz, Shushant Jain, E. Whitney Evans et al. · Neuron · 2004 · 2.4K citations · Full text

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

Javier Simón‐Sánchez, Claudia Schulte, José Brás et al. · Nature Genetics · 2009 · 1.9K citations · Full text

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