Concepedia

Two Novel α7 Nicotinic Acetylcholine Receptor Ligands: In Vitro Properties and Their Efficacy in Collagen-Induced Arthritis in Mice

Marjolein A. van Maanen, Roger L. Papke, Frieda A. Koopman, Jessica Koepke, Lisette Bevaart, Roger B. Clark, Diana Lamppu, Daniel Elbaum, Gregory J. LaRosa, Paul P. Tak,

PLoS ONE · 2015 · 44 citations · 42 references

DOIFull text

Open access

Abstract

These data provide direct evidence that the α7nAChR in immune cells does not require typical ion channel activation to exert its antiinflammatory effects.

References

42

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

L. V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al. · Nature · 2000 · 4K citations

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Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

Wouter J. de Jonge, Esmerij P. van der Zanden, Frans Olivier The et al. · Nature Immunology · 2005 · 1.1K citations

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A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization

Raymond S Hurst, Mihály Hajós, M. Raggenbass et al. · Journal of Neuroscience · 2005 · 441 citations · Full text

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The Vagus Nerve: A Tonic Inhibitory Influence Associated With Inflammatory Bowel Disease in a Murine Model

Jean‐Eric Ghia, Patricia Blennerhassett, Harry Kumar–Ondiveeran et al. · Gastroenterology · 2006 · 390 citations · Full text

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The Vagus Nerve and Nicotinic Receptors Modulate Experimental Pancreatitis Severity in Mice

David J. van Westerloo, Ilona A. J. Giebelen, Sandrine Florquin et al. · Gastroenterology · 2006 · 374 citations

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