Roger B. Clark

Fluorocyclines. 1. 7-Fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: A Potent, Broad Spectrum Antibacterial Agent

Xiao-Yi Xiao, Diana K. Hunt, Jingye Zhou et al. · Journal of Medicinal Chemistry · 2011 · 123 citations

Tetracycline Antibacterial Agents, Medicinal Chemistry, Bioorganic Chemistry +14

Fluorocyclines. 2. Optimization of the C-9 Side-Chain for Antibacterial Activity and Oral Efficacy

Roger B. Clark, Diana K. Hunt, Minsheng He et al. · Journal of Medicinal Chemistry · 2011 · 71 citations

Medicinal Chemistry, Allergy, Antibiotics +14

Synthesis and Antibacterial Activity of Pentacyclines: A Novel Class of Tetracycline Analogs

Cuixiang Sun, Diana K. Hunt, Roger B. Clark et al. · Journal of Medicinal Chemistry · 2011 · 62 citations · Full text

Medicinal Chemistry, Heterocyclic, Antibacterial Activity Diverse +15

Process R&D of Eravacycline: The First Fully Synthetic Fluorocycline in Clinical Development

Magnus Rönn, Zhijian Zhu, Philip C. Hogan et al. · Organic Process Research & Development · 2013 · 59 citations

Pharmaceutical Science, Organic Chemistry, Pharmacotherapy +19

Two Novel α7 Nicotinic Acetylcholine Receptor Ligands: In Vitro Properties and Their Efficacy in Collagen-Induced Arthritis in Mice

Marjolein A. van Maanen, Roger L. Papke, Frieda A. Koopman et al. · PLoS ONE · 2015 · 44 citations · Full text