1,5‐Anhydrohexitol Nucleic Acids, a New Promising Antisense Construct

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Peter E. Nielsen, Rolf H. Berg, Ole Buchardt · Science · 1991 · 3.3K citations

Life Sciences, Biomolecular Engineering, Molecular Biology +17

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 736 citations

Life Sciences, Biochemistry, Molecular Biology +12

Sequence‐Specific Recognition and Modification of Double‐Helical DNA by Oligonucleotides

Nguyen T. Thuong, Claude Hélène · Angewandte Chemie International Edition in English · 1993 · 624 citations

Life Sciences, Biochemistry, Molecular Biology +15

Modified deoxyoligonucleotides stable to exonuclease degradation in serum

Jeng‐Pyng Shaw, Kenneth M. Kent, Jeff Bird et al. · Nucleic Acids Research · 1991 · 369 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The synthesis of modified oligonucleotides by the phosphoramidite approach and their applications

Serge L. Beaucage, Radhakrishnan P. Iyer · Tetrahedron · 1993 · 318 citations

Pharmacy, Biotechnology, Molecular Biology +12