Arthur Van Aerschot

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Jesper B. Bramsen, Maria Bach Laursen, A. Nielsen et al. · Nucleic Acids Research · 2009 · 349 citations · Full text

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides

Ilse Verheggen, Arthur Van Aerschot, Suzanne Toppet et al. · Journal of Medicinal Chemistry · 1993 · 150 citations

Cyclohexene Nucleic Acids (CeNA):  Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

Jing Wang, Birgit Verbeure, Ingrid Luyten et al. · Journal of the American Chemical Society · 2000 · 135 citations

1′, 5′ ‐Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides

Chris Hendrix, Helmut Rosemeyer, Ilse Verheggen et al. · Chemistry - A European Journal · 1997 · 133 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Biochemistry +13

Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides

Piet Herdewijn, Jan Balzarini, Rudi Pauwels et al. · Journal of Medicinal Chemistry · 1988 · 117 citations