Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics

Shao‐En Ong, Blagoy Blagoev, Irina Kratchmarova, +4

Molecular & Cellular Proteomics

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

Steven P. Gygi, Beate Rist, Scott A. Gerber, +3

Nature Biotechnology

Protein ChemistryBiochemistryComplex Protein MixturesProtein FoldingMedicine +8

Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents

Philip L. Ross, Yulin Huang, Jason Marchese, +14

Molecular & Cellular Proteomics

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

Joshua E. Elias, Steven P. Gygi

Nature Methods

Natural SciencesLarge-scale Protein IdentificationsMedicineMass SpectrometryComputational Biology +10

Tandem Mass Tags:  A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

Andrew Thompson, Jürgen Schäfer, Karsten Kuhn, +5

Analytical Chemistry

Biological Mass SpectrometryMolecular BiologyTandem Mass TagsBioanalysisTandem Mass Spectrometry +19

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

Scott A. Gerber, A. John Rush, Olaf Stemman, +2

Proceedings of the National Academy of Sciences

Parts per Million Mass Accuracy on an Orbitrap Mass Spectrometer via Lock Mass Injection into a C-trap

Jesper V. Olsen, Lyris Martins Franco de Godoy, Guoqing Li, +7

Molecular & Cellular Proteomics

EngineeringLock Mass InjectionBiological Mass SpectrometrySpectrochemical AnalysisMillion Mass Accuracy +15

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham, +18

Nature Biotechnology

Quantitative Chemical ProteomicsBiochemistryMedicineNatural SciencesProteomics +7

Accurate quantitation of protein expression and site-specific phosphorylation

Yoshiya Oda, Kimberly N. Huang, Frederick R. Cross, +2

Proceedings of the National Academy of Sciences

Abundance DifferencesBiological Mass SpectrometryMolecular BiologyMass Spectrometry-based MethodProtein Expression +15

Higher-energy C-trap dissociation for peptide modification analysis

Jesper V. Olsen, Boris Maček, Oliver Lange, +3

Nature Methods

Peptide LibraryPeptide Modification AnalysisBiochemistryPeptide Synthesis