Proteome survey reveals modularity of the yeast cell machinery

Anne‐Claude Gavin, Patrick Aloy, Paola Grandi, +29

Nature

Proteomic TechnologyNatural SciencesProteasomeMolecular BiologyYeast +3

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham, +18

Nature Biotechnology

Quantitative Chemical ProteomicsBiochemistryMedicineNatural SciencesProteomics +7

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Marcus Bantscheff, Carsten Hopf, Mikhail M. Savitski, +21

Nature Biotechnology

Chemoproteomics ProfilingMolecular CharacterizationDrug TargetBiochemistryHdac Complexes +8

Confident Phosphorylation Site Localization Using the Mascot Delta Score

Mikhail M. Savitski, Simone Lemeer, Markus Böesche, +4

Molecular & Cellular Proteomics

Robust and Sensitive iTRAQ Quantification on an LTQ Orbitrap Mass Spectrometer

Marcus Bantscheff, Markus Böesche, Dirk Eberhard, +3

Molecular & Cellular Proteomics

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson, +29

Nature

Drug TargetCyclin-dependent Kinase 12Parasitic ProtozoaMedicineImmunology +7

Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds

Gregory J. Crowther, Heidi K. Hillesland, Katelyn R. Keyloun, +19

PLoS ONE

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Michael G. Thomas, Manu De Rycker, Myriam Ajakane, +49

Journal of Medicinal Chemistry

Translational MedicineMedicinal ChemistryLeishmania DonovaniNew Candidate DrugsParasitic Protozoa +12

Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics

Gérard Joberty, Markus Böesche, Jack A. Brown, +15

ACS Chemical Biology

Drug TargetBioorganic ChemistryMolecular BiologyChemical BiologyRedox Biology +15

Functional organization of the yeast proteome by systemic analysis of protein complexes

Anne‐Claude Gavin, Paola Grandi, Markus Böesche, +4

GBM Annual Fall meeting Halle 2002

Protein FunctionYeast ProteomeBiochemistryProtein FoldingNatural Sciences +9