Involvement of Gi/o Proteins in Nerve Growth Factor-Stimulated Phosphorylation and Degradation of Tuberin in PC-12 Cells and Cortical Neurons

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

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Signal Transduction, Control Cell Growth, Cell Division +10

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3K citations

Signal Transduction, Signaling Pathway, Cell Regulation +5

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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Signal Transduction, Developmental Biology, Molecular Physiology +10

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

Ryoji Yao, Geoffrey M. Cooper · Science · 1995 · 1.4K citations

Apoptosis, Cell Death, Cell Proliferation +17

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

Andrew R. Tee, Diane C. Fingar, Brendan D. Manning et al. · Proceedings of the National Academy of Sciences · 2002 · 825 citations · Full text

Molecular Biology, Rapamycin-resistant Mutants, Cytoskeleton +16