Concepedia

Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity

Brian M. Smith, Jeffrey M. Smith, James H. Tsai, Jeffrey A. Schultz, Charles A. Gilson, Scott A. Estrada, Rita R. Chen, Douglas M. Park, Emily B. Prieto, Charlemagne S. Gallardo,

Bioorganic & Medicinal Chemistry Letters · 2005 · 85 citations · 13 references

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13

Valvular Heart Disease Associated with Fenfluramine–Phentermine

Heidi M. Connolly, Jack L. Crary, Michael D. McGoon et al. · New England Journal of Medicine · 1997 · 1.6K citations · Full text

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Laurence H. Tecott, Linda M. Sun, Susan F. Akana et al. · Nature · 1995 · 1.3K citations

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Evidence for Possible Involvement of 5-HT<sub>2B</sub>Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

Richard B. Rothman, Michael H. Baumann, Jason E. Savage et al. · Circulation · 2000 · 692 citations · Full text

Possible Role of Valvular Serotonin 5-HT2B Receptors in the Cardiopathy Associated with Fenfluramine

Lawrence W. Fitzgerald, Timothy C. Burn, Barry S. Brown et al. · Molecular Pharmacology · 2000 · 428 citations · Full text

5-HT2C Receptor Agonists: Pharmacological Characteristics and Therapeutic Potential

Joel R. Martin, Michael Bös, F. Jenck et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 334 citations