Food-Specific Serum IgG4 and IgE Titers to Common Food Antigens in Irritable Bowel Syndrome

Abstract

Serum IgG4 antibodies to common foods like wheat, beef, pork, and lamb are elevated in IBS patients. In keeping with the observation in other atopic conditions, this finding suggests the possibility of a similar pathophysiological role for IgG4 antibodies in IBS.